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Midfoot Sprain (Lisfranc / Cuneiform)

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1 · SNAPSHOT

Midfoot Sprain (Lisfranc / Cuneiform) body chart
Illustrative, not diagnostic. Canva body chart for Midfoot Sprain (Lisfranc / Cuneiform).

Who: A twist or an axial load — a landing, a step-off, a foot that got trodden on, a fall onto a plantarflexed foot.
What: Ligamentous injury of the tarsometatarsal complex, with or without fracture, with or without instability.
How it behaves: Midfoot pain and swelling. Difficulty weight-bearing or pushing off. Worse on stairs, pivoting and uneven ground. Often described as "my foot felt like it folded."

The one thing to take from this page:

"Plantar bruise = Lisfranc until proven otherwise." And a normal plain film is not a normal midfoot.

Why this one gets missed

The problemThe consequence
Low-velocity injuries are commonly subtleThe story sounds benign
Plain films may miss subtle injuryA normal report reassures the wrong way
Radiographic criteria vary — no single universally applied rule [1]There is no clean number to hide behind
Delayed diagnosisChronic pain · arch collapse · post-traumatic arthritis · poor push-off

⚠️ No guideline exists. And the systematic review of radiographic criteria finds no single universally applied rule — that is the finding, not a gap in the research. Clinical suspicion carries this decision.

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Guideline anchor

No guideline exists for Lisfranc injury, in Australia or anywhere.

More

Anchored to the current diagnostic and management review (Hammad et al. 2026, PMID 41522288), the systematic review of radiographic diagnostic criteria (Seow et al. 2023, PMID 38012651), and the randomised trial of operative versus non-operative care in non-displaced injuries (Ponkilainen et al. 2025, PMID 39584430).

PubMed Source

There is no guideline and — more importantly — the systematic review of radiographic criteria finds no single universally applied rule for diagnosing this injury. That is the finding, not a gap in this page's research. Clinical suspicion and imaging escalation carry the decision, and the page says so.

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Verified diagnostic accuracy, where the evidence stands and what it doesn't settle. Free with an account.

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Sources · 18

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Every source on this page resolves and title-verifies against PubMed. Newest first.

  1. 2023Seow et al. (2023). Inconsistent radiographic diagnostic criteria for lisfranc injuries: a systematic review. BMC musculoskeletal disorders, 24(1), 915. https://doi.org/10.1186/s12891-023-07043-z
  2. 2024Tang et al. (2024). Comparison of diagnostic performance of X‑ray, CT and MRI in patients with surgically confirmed subtle Lisfranc injuries. Experimental and therapeutic medicine, 27(4), 174. https://doi.org/10.3892/etm.2024.12462
  3. 2009Raikin et al. (2009). Prediction of midfoot instability in the subtle Lisfranc injury. Comparison of magnetic resonance imaging with intraoperative findings. The Journal of bone and joint surgery. American volume, 91(4), 892-9. https://doi.org/10.2106/JBJS.H.01075
  4. 2021Ponkilainen et al. (2021). Outcomes after nonoperatively treated non-displaced Lisfranc injury: a retrospective case series of 55 patients. Archives of orthopaedic and trauma surgery, 141(8), 1311-1317. https://doi.org/10.1007/s00402-020-03599-w
  5. 2025Ponkilainen et al. (2025). Operative versus non-operative treatment for non-displaced Lisfranc injuries: A two-center randomized clinical trial. Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society, 114(2), 153-161. https://doi.org/10.1177/14574969241295585
  6. 2002Nunley & Vertullo (2002). Classification, investigation, and management of midfoot sprains: Lisfranc injuries in the athlete. The American journal of sports medicine, 30(6), 871-8. https://doi.org/10.1177/03635465020300061901
  7. 2006Ly & Coetzee (2006). Treatment of primarily ligamentous Lisfranc joint injuries: primary arthrodesis compared with open reduction and internal fixation. A prospective, randomized study. The Journal of bone and joint surgery. American volume, 88(3), 514-20. https://doi.org/10.2106/JBJS.E.00228
  8. 2010Stavlas et al. (2010). The role of reduction and internal fixation of Lisfranc fracture-dislocations: a systematic review of the literature. International orthopaedics, 34(8), 1083-91. https://doi.org/10.1007/s00264-010-1101-x
  9. 2019Han et al. (2019). Comparison of primary arthrodesis versus open reduction with internal fixation for Lisfranc injuries: Systematic review and meta-analysis. Journal of postgraduate medicine, 65(2), 93-100. https://doi.org/10.4103/jpgm.JPGM_414_18
  10. 2021Attia et al. (2021). Return to Play After Low-Energy Lisfranc Injuries in High-Demand Individuals: A Systematic Review and Meta-Analysis of Athletes and Active Military Personnel. Orthopaedic journal of sports medicine, 9(3), 2325967120988158. https://doi.org/10.1177/2325967120988158
  11. 2023Talaski et al. (2023). Weightbearing Computed Tomography vs Conventional Tomography for Examination of Varying Degrees of Lisfranc Injures: A Systematic Review of the Literature. Foot & ankle orthopaedics, 8(4), 24730114231209767. https://doi.org/10.1177/24730114231209767
  12. 2024O'Connor et al. (2024). Primary arthrodesis versus open reduction internal fixation for acute Lisfranc injuries: a systematic review and meta-analysis. Archives of orthopaedic and trauma surgery, 145(1), 49. https://doi.org/10.1007/s00402-024-05700-z
  13. 2025Rajivan et al. (2025). High rates of return to sport following suture button fixation for ligamentous Lisfranc injuries: A systematic review. World journal of orthopedics, 16(3), 97830. https://doi.org/10.5312/wjo.v16.i3.97830
  14. 2025Ukita et al. (2025). Diagnosis and assessment of subtle Lisfranc injuries: Comparison of computed tomography and weight-bearing radiography. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 30(6), 1133-1136. https://doi.org/10.1016/j.jos.2025.04.004
  15. 2025Poulsen et al. (2025). Prospective Validation of a Weightbearing CT Stability Threshold for Subtle Lisfranc Injuries. Foot & ankle international, 46(12), 1386-1394. https://doi.org/10.1177/10711007251374674
  16. 2025Mohamed et al. (2025). From Missed Diagnosis to Optimal Outcomes: A Comprehensive Review of Lisfranc Injuries. Cureus, 17(10), e94615. https://doi.org/10.7759/cureus.94615
  17. 2026Semelsberger et al. (2026). Diagnostic evaluation and nonoperative management of Lisfranc injuries in athletes. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 34(9), 3079-3088. https://doi.org/10.1002/ksa.70244
  18. 2026Hammad et al. (2026). Lisfranc Injuries: Latest Updates on Diagnostics and Management. Translational sports medicine, 2026, 3933956. https://doi.org/10.1155/tsm2/3933956

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