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1 · SNAPSHOT

Migraine body chart
Illustrative, not diagnostic. Canva body chart for Migraine.

You won't cure it, and there are three things you can do that matter.

Illness script in one line: unilateral throbbing headache lasting 4 to 72 hours, moderate to severe, made worse by routine physical activity, with nausea and both light and sound sensitivity, sometimes preceded by aura.

Caseload frequency: you will see migraineurs constantly, usually presenting for something else. Read further: prevalence, disease burden and the need for preventive therapy [1], prevalence and burden [2].

The three things this page is actually for

1. Recognise it, so you don't treat it as a neck. Every row of the migraine picture is the opposite of tension-type headache [3].

2. Know that migraine with aura and cervical artery dissection have been studied together [4]. It changes what you do before you touch a neck.

3. Know that exercise is a preventive intervention, not just kindness. Read further: network meta-analysis of exercise interventions [5].

Everything else — triptans, CGRP therapies, prophylaxis — you refer.

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Guideline anchor

No Australian guideline for this presentation. Anchored to The Australian anchor is Australian Prescriber's migraine management article (Jenkins et al. 2020, PMID 33093740) — not a formal clinical practice guideline, and the page says so.

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The pharmacological anchors are the evidence-based guidelines for the pharmacological treatment of migraine in Cephalalgia (Ornello et al. 2025, PMID 40277321), the International Headache Society global practice recommendations for acute pharmacological treatment (Puledda et al. 2024, PMID 39133176) and the 2025 guideline update to acute treatment (Robblee et al. 2026, PMID 41321235). The physiotherapy anchor is a network meta-analysis of exercise interventions for migraine in Headache (Reina-Varona et al. 2024, PMID 38597252). The safety anchor for anyone considering cervical treatment is a systematic review and meta-analysis of migraine, migraine aura and cervical artery dissection (Rist et al. 2011, PMID 21511950).

PubMed Source

The guidelines here are pharmacological and written for prescribers. There is no physiotherapy management guideline for migraine. The Australian Prescriber article is a practice review, not a clinical practice guideline.

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Verified diagnostic accuracy, where the evidence stands and what it doesn't settle. Free with an account.

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Sources · 20

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Every source on this page resolves and title-verifies against PubMed. Newest first.

  1. 2007Lipton et al. (2007). Migraine prevalence, disease burden, and the need for preventive therapy. Neurology, 68(5), 343-9. https://doi.org/10.1212/01.wnl.0000252808.97649.21
  2. 2024Cohen et al. (2024). Prevalence and burden of migraine in the United States: A systematic review. Headache, 64(5), 516-532. https://doi.org/10.1111/head.14709
  3. 2023Onan et al. (2023). Debate: differences and similarities between tension-type headache and migraine. The journal of headache and pain, 24(1), 92. https://doi.org/10.1186/s10194-023-01614-0
  4. 2011Rist et al. (2011). Migraine, migraine aura, and cervical artery dissection: a systematic review and meta-analysis. Cephalalgia : an international journal of headache, 31(8), 886-96. https://doi.org/10.1177/0333102411401634
  5. 2024Reina-Varona et al. (2024). Efficacy of various exercise interventions for migraine treatment: A systematic review and network meta-analysis. Headache, 64(7), 873-900. https://doi.org/10.1111/head.14696
  6. 2023Ashina et al. (2023). Medication overuse headache. Nature reviews. Disease primers, 9(1), 5. https://doi.org/10.1038/s41572-022-00415-0
  7. 2024Khoo et al. (2024). Acute and preventive treatment of menstrual migraine: a meta-analysis. The journal of headache and pain, 25(1), 143. https://doi.org/10.1186/s10194-024-01848-6
  8. 2020Tiseo et al. (2020). Migraine and sleep disorders: a systematic review. The journal of headache and pain, 21(1), 126. https://doi.org/10.1186/s10194-020-01192-5
  9. 2012Lempert et al. (2012). Vestibular migraine: diagnostic criteria. Journal of vestibular research : equilibrium & orientation, 22(4), 167-72. https://doi.org/10.3233/VES-2012-0453
  10. 2025Tu et al. (2025). Prevalence, Clinical Correlates, and Functional Implications of Vestibular Symptoms in Patients With Migraine. Neurology, 105(9), e214248. https://doi.org/10.1212/WNL.0000000000214248
  11. 2024Villar-Martinez & Goadsby (2024). Vestibular migraine: an update. Current opinion in neurology, 37(3), 252-263. https://doi.org/10.1097/WCO.0000000000001257
  12. 2019Do et al. (2019). Red and orange flags for secondary headaches in clinical practice: SNNOOP10 list. Neurology, 92(3), 134-144. https://doi.org/10.1212/WNL.0000000000006697
  13. 2025Dominguez et al. (2025). Magnesium and Migraine. Nutrients, 17(4). https://doi.org/10.3390/nu17040725
  14. 2015Cameron et al. (2015). Triptans in the Acute Treatment of Migraine: A Systematic Review and Network Meta-Analysis. Headache, 55 Suppl 4, 221-35. https://doi.org/10.1111/head.12601
  15. 2024Charles et al. (2024). Calcitonin gene-related peptide-targeting therapies are a first-line option for the prevention of migraine: An American Headache Society position statement update. Headache, 64(4), 333-341. https://doi.org/10.1111/head.14692
  16. 2025Ornello et al. (2025). Evidence-based guidelines for the pharmacological treatment of migraine, summary version. Cephalalgia : an international journal of headache, 45(4), 3331024251321500. https://doi.org/10.1177/03331024251321500
  17. 2024Puledda et al. (2024). International Headache Society global practice recommendations for the acute pharmacological treatment of migraine. Cephalalgia : an international journal of headache, 44(8), 3331024241252666. https://doi.org/10.1177/03331024241252666
  18. 2026Robblee et al. (2026). 2025 guideline update to acute treatment of migraine for adults in the emergency department: The American Headache Society evidence assessment of parenteral pharmacotherapies. Headache, 66(1), 53-76. https://doi.org/10.1111/head.70016
  19. 2020Jenkins (2020). Migraine management. Australian prescriber, 43(5), 148-151. https://doi.org/10.18773/austprescr.2020.047
  20. 2023Zhang & Robbins (2023). Migraine. Annals of internal medicine, 176(1), ITC1-ITC16. https://doi.org/10.7326/AITC202301170

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