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Fracture / Osteochondral Lesion / Infection — the ankle safety screen

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Three branches, and they do not share a timeline:

BranchWhen it declares itselfWhat answers it
FractureDay oneThe rule, then the radiograph
Osteochondral lesion of the talusWeek six to twelve, when the sprain won't settleMRI, and orthopaedic review
InfectionAny time at allClinical suspicion, then urgent medical assessment

The one thing to take from this page:

A negative Ottawa rule and a negative X-ray both clear a fracture — and nothing else.

You'll often be taught this as a day-one screen. Two of the three branches aren't.

Fracture is a day-one decision, and the Ottawa Ankle Rules are built for exactly that. The osteochondral lesion is not — it hides inside a sprain that isn't settling, and cartilage and osteochondral lesions are not rare after acute ligamentous ankle injury [1]. Infection has no timeline at all.

⚠️ No national Australian guideline governs this decision; NSW's emergency care protocol (Agency for Clinical Innovation) uses the Ottawa Ankle Rules for it. The Ottawa Ankle Rules are a decision rule about whether to X-ray, anchored to Bachmann et al. 2003 [2] and Gomes et al. 2022 [3]. Imaging referral rights differ by state and setting — check what you are permitted to request where you are working.

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Guideline anchor

No national Australian guideline governs acute ankle imaging decisions in physiotherapy; NSW's emergency care protocol (Agency for Clinical Innovation, 2023) uses the Ottawa Ankle Rules for the X-ray decision.

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The rule's evidence is anchored to the classic systematic review (Bachmann et al. 2003, PMID 12595378) and the updated adult meta-analysis (Gomes et al. 2022, PMID 36151550). The infection limb is anchored to the IWGDF/IDSA diabetes-related foot infection guideline (Senneville et al. 2023, PMID 37779457) and, for the joint, to the septic arthritis current-concepts review (Sanpera et al. 2025, PMID 39758603). Apart from the NSW protocol, all non-Australian.

PubMed Source

The Ottawa Ankle Rules are a decision rule about whether to X-ray, not a guideline about what a physiotherapist does next. Beyond the NSW emergency protocol there is no Australian equivalent, no Australian physiotherapy imaging-referral standard that covers every jurisdiction, and imaging referral rights differ by state and setting. Check what you are permitted to request where you are working — the page teaches the reasoning, not the paperwork.

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Sources · 19

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Every source on this page resolves and title-verifies against PubMed. Newest first.

  1. 2025Baltes et al. (2025). The Prevalence, Size, and Anatomic Location of Cartilage and Osteochondral Lesions in Athletes With an Acute Ligamentous Ankle Injury. The American journal of sports medicine, 53(9), 2173-2180. https://doi.org/10.1177/03635465251344187
  2. 2003Bachmann et al. (2003). Accuracy of Ottawa ankle rules to exclude fractures of the ankle and mid-foot: systematic review. BMJ (Clinical research ed.), 326(7386), 417. https://doi.org/10.1136/bmj.326.7386.417
  3. 2022Gomes et al. (2022). Diagnostic accuracy of the Ottawa ankle rule to exclude fractures in acute ankle injuries in adults: a systematic review and meta-analysis. BMC musculoskeletal disorders, 23(1), 885. https://doi.org/10.1186/s12891-022-05831-7
  4. 2022Weaver et al. (2022). Magnetic resonance imaging of musculoskeletal infections. Polish journal of radiology, 87, e141-e162. https://doi.org/10.5114/pjr.2022.113825
  5. 2023Crowell et al. (2023). Diagnostic Imaging for Distal Extremity Injuries in Direct Access Physical Therapy: An Observational Study. International journal of sports physical therapy, 18(2), 431-438. https://doi.org/10.26603/001c.73314
  6. 2023Anastasio et al. (2023). Juvenile Osteochondral Lesions of the Talus: Current Concepts Review and an Update on the Literature. Children (Basel, Switzerland), 10(5). https://doi.org/10.3390/children10050884
  7. 2023Steele et al. (2023). Republication of "Osteochondral Lesions of the Talus: Current Concepts in Diagnosis and Treatment". Foot & ankle orthopaedics, 8(3), 24730114231192961. https://doi.org/10.1177/24730114231192961
  8. 2023Senneville et al. (2023). IWGDF/IDSA Guidelines on the Diagnosis and Treatment of Diabetes-related Foot Infections (IWGDF/IDSA 2023). Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. https://doi.org/10.1093/cid/ciad527
  9. 2023Tansey et al. (2023). Current concepts in ankle fractures. Journal of clinical orthopaedics and trauma, 45, 102260. https://doi.org/10.1016/j.jcot.2023.102260
  10. 2024Anastasio et al. (2024). Osteochondral Lesions of the Talus: Etiology, Clinical Presentation, Treatment Options, and Outcomes. Foot and ankle clinics, 29(2), 193-211. https://doi.org/10.1016/j.fcl.2023.11.002
  11. 2024Maity et al. (2024). A systematic review of diabetic foot infections: pathogenesis, diagnosis, and management strategies. Frontiers in clinical diabetes and healthcare, 5, 1393309. https://doi.org/10.3389/fcdhc.2024.1393309
  12. 2024Zaki & Morrison (2024). Osteomyelitis and Septic Arthritis of the Foot and Ankle: Imaging Update. Clinics in podiatric medicine and surgery, 41(4), 745-758. https://doi.org/10.1016/j.cpm.2024.04.007
  13. 2024Butler et al. (2024). Presurgical and Postsurgical MRI Evaluation of Osteochondral Lesions of the Foot and Ankle: A Primer. Clinics in podiatric medicine and surgery, 41(4), 759-773. https://doi.org/10.1016/j.cpm.2024.04.008
  14. 2024Lewis et al. (2024). Rehabilitation for ankle fractures in adults. The Cochrane database of systematic reviews, 9(9), CD005595. https://doi.org/10.1002/14651858.CD005595.pub4
  15. 2024Cheng & Wang (2024). Advancements in the treatment of osteochondral lesions of the talus. Journal of orthopaedic surgery and research, 19(1), 827. https://doi.org/10.1186/s13018-024-05314-6
  16. 2025Sanpera et al. (2025). Diagnosis and management of septic arthritis: A current concepts review. Journal of children's orthopaedics, 19(1), 14-19. https://doi.org/10.1177/18632521241311302
  17. 2025Krez et al. (2025). Fracture-Related Infections in the Foot and Ankle. Foot and ankle clinics, 30(1), 191-200. https://doi.org/10.1016/j.fcl.2024.06.011
  18. 2025Carvalho et al. (2025). Ottawa Ankle Rules: A Reliable Clinical Instrument to Detect Fractures in Children and Adolescents. Revista brasileira de ortopedia, 60(1), s00441800938. https://doi.org/10.1055/s-0044-1800938
  19. 2025Wang & Li (2025). Early weight-bearing after ankle fracture surgery: a systematic review and meta-analysis of functional outcomes and safety. Journal of orthopaedic surgery and research, 20(1), 785. https://doi.org/10.1186/s13018-025-06216-x

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