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Sesamoiditis

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1 · SNAPSHOT

Sesamoiditis body chart
Illustrative, not diagnostic. Canva body chart for Sesamoiditis.

Who: Runners, especially forefoot strikers, dancers, jumpers, and anyone in high heels. Common in young athletes.
What: Load intolerance of the sesamoid complex under the first metatarsal head — or one of six specific things that present identically.
How it behaves: Localised plantar pain under the ball of the great toe. "Bruised." Worse with running, jumping, push-off and high heels. Eased by offloading and a supportive, stiff-soled shoe.

The one thing to take from this page:

"Sesamoiditis" is a reasonable starting label and a poor finishing one. Persistent focal pain here has a differential you have to actually go and check.

What sits underneath the label

If it isn't settling, this is the list
Sesamoid stress fracture · fracture nonunion · avascular necrosis
Painful bipartite sesamoid · plantar plate / turf toe injury
Gout, inflammatory disease, or infection

Image when there is: persistent focal pain · night or rest pain · swelling · traumatic onset · failure to improve · a high-demand athlete or dancer.

⚠️ No guideline exists, anywhere. Anchored to a systematic review with pooled individual data [1] and a Delphi consensus [2] — which is structured expert opinion, not evidence, and is labelled that way.

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Guideline anchor

No guideline exists for sesamoiditis, in Australia or anywhere.

More

Anchored to the systematic review with pooled individual data on conservative care (Biz et al. 2025, PMID 40731844) and the Delphi content-validity recommendations for assessment and management (Stewart et al. 2024, PMID 38820171), which is the closest thing to a consensus statement this condition has.

PubMed Source

A Delphi consensus is expert opinion structured, not evidence, and it is labelled that way here. The conservative-care evidence is limited but clinically consistent. There is no Australian guidance and no guideline anywhere.

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Verified diagnostic accuracy, where the evidence stands and what it doesn't settle. Free with an account.

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Sources · 20

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Every source on this page resolves and title-verifies against PubMed. Newest first.

  1. 2025Biz et al. (2025). Conservative Treatment of Sesamoiditis: A Systematic Literature Review with Individual-Level Pooled Data Analysis. Medicina (Kaunas, Lithuania), 61(7). https://doi.org/10.3390/medicina61071215
  2. 2024Stewart et al. (2024). The development of recommendations for the assessment and management of sesamoiditis by podiatrists: A Delphi and content validity study. Journal of foot and ankle research, 17(2), e12025. https://doi.org/10.1002/jfa2.12025
  3. 2015Schein et al. (2015). Turf toe and sesamoiditis: what the radiologist needs to know. Clinical imaging, 39(3), 380-9. https://doi.org/10.1016/j.clinimag.2014.11.011
  4. 2024Choi et al. (2024). Atraumatic Sport-Related Medial Sesamoid Pain: Conservative Treatment Outcome and Magnetic Resonance Imaging Features. Clinics in orthopedic surgery, 16(4), 641-649. https://doi.org/10.4055/cios24037
  5. 2012Bichara et al. (2012). Sesamoidectomy for hallux sesamoid fractures. Foot & ankle international, 33(9), 704-6. https://doi.org/10.3113/FAI.2012.0704
  6. 2012Sharma et al. (2012). Utility of (99m)Tc-MDP SPECT-CT for the diagnosis of sesamoiditis as cause of metatarsalgia. Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India, 27(1), 45-7. https://doi.org/10.4103/0972-3919.108865
  7. 2013Nwawka et al. (2013). Sesamoids and accessory ossicles of the foot: anatomical variability and related pathology. Insights into imaging, 4(5), 581-93. https://doi.org/10.1007/s13244-013-0277-1
  8. 2014Sims & Kurup (2014). Painful sesamoid of the great toe. World journal of orthopedics, 5(2), 146-50. https://doi.org/10.5312/wjo.v5.i2.146
  9. 2018Shimozono et al. (2018). Sesamoidectomy for Hallux Sesamoid Disorders: A Systematic Review. The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons, 57(6), 1186-1190. https://doi.org/10.1053/j.jfas.2018.03.044
  10. 2020Hallinan et al. (2020). High-Resolution MRI of the First Metatarsophalangeal Joint: Gross Anatomy and Injury Characterization. Radiographics : a review publication of the Radiological Society of North America, Inc, 40(4), 1107-1124. https://doi.org/10.1148/rg.2020190145
  11. 2020Lombard et al. (2020). Hallux sesamoid complex imaging: a practical diagnostic approach. Skeletal radiology, 49(12), 1889-1901. https://doi.org/10.1007/s00256-020-03507-8
  12. 2020Dean et al. (2020). Functional Outcome of Sesamoid Excision in Athletes. The American journal of sports medicine, 48(14), 3603-3609. https://doi.org/10.1177/0363546520962518
  13. 2021Andrews et al. (2021). Diagnosis and conservative management of great toe pathologies: a review. Postgraduate medicine, 133(4), 409-420. https://doi.org/10.1080/00325481.2021.1895587
  14. 2022Sugimoto et al. (2022). Hallux Sesamoid Injury Characteristics in Young Athletes Presented to the Sports Medicine Clinic. Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 32(3), e276-e280. https://doi.org/10.1097/JSM.0000000000000902
  15. 2022Carroll et al. (2022). Forefoot Injuries in Athletes: Integration of the Movement System. International journal of sports physical therapy, 17(1), 81-89. https://doi.org/10.26603/001c.30021
  16. 2022Chen et al. (2022). High-Resolution Ultrasound of the Forefoot and Common Pathologies. Diagnostics (Basel, Switzerland), 12(7). https://doi.org/10.3390/diagnostics12071541
  17. 2023Kaur et al. (2023). The assessment and management of sesamoiditis: a focus group study of podiatrists in Aotearoa New Zealand. Journal of foot and ankle research, 16(1), 29. https://doi.org/10.1186/s13047-023-00628-w
  18. 2023Lim & Liem (2023). First Metatarsophalangeal Joint Pain in Athletes: Diagnosis, Management, and Return to Play Considerations. Current sports medicine reports, 22(6), 217-223. https://doi.org/10.1249/JSR.0000000000001076
  19. 2025Artioli et al. (2025). Hallux Sesamoid Nonunion: A Comprehensive Systematic Review of Current Evidence. Journal of personalized medicine, 15(8). https://doi.org/10.3390/jpm15080342
  20. 2025Nakajima (2025). Avoiding Hallux Sesamoidectomy: A Narrative Review. Journal of clinical medicine, 14(21). https://doi.org/10.3390/jcm14217687

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