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Freiberg's Disease (2nd metatarsal head osteonecrosis)

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1 · SNAPSHOT

Freiberg's Disease (2nd metatarsal head osteonecrosis) body chart
Illustrative, not diagnostic. Canva body chart for Freiberg's Disease (2nd metatarsal head osteonecrosis).

Rare, and the reason it is here is that getting it wrong means loading a dying bone.

Illness script in one line: dorsal forefoot pain over the second metatarsal head with local swelling and a stiffening MTP joint, in an adolescent or young adult — classically a female dancer — building over weeks to months without a single injury.

Caseload frequency: rare. You will meet far more metatarsalgia, stress fracture and Morton's neuroma — which is exactly the problem, because this one hides inside those labels.

Everything else in the forefoot gets loaded. This one gets offloaded.

This is the organising idea, and it is the single most important thing on the page.

Freiberg's is osteonecrosis of a metatarsal head — most often the second. The management line is offload + relative rest, then gradual reload once pain-free. That is the opposite instruction from almost every other page in this region, where the answer to a load-related problem is graded loading.

The forefoot page you're used toThis page
Tendinopathy, plantar fasciopathy, metatarsalgia → load it, progressivelyBone that is losing its blood supply → take load off it
Pain is a guide to dosagePain is a signal to unload
Progress on the 24-hour responseProgress only once pain-free, and slowly

A student who applies standard tendon reasoning here does real harm. That is why it is worth a page.

And it has a shape you can spot

Read further: bilateral disease in a young female dancer [1], a rare cause of chronic foot pain [2].

Adolescent and young female dancers. Add the mechanical version of that: repetitive high load through a dorsiflexed second MTP joint — dancing en pointe or demi-pointe, running, gymnastics, and a long second metatarsal.

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Guideline anchor

No Australian guideline and no clinical practice guideline of any kind.

More

The closest thing is an evidence-based treatment algorithm published in Cartilage (Yoshimura et al. 2024, PMID 37815268), with reviews of treatment (Seybold et al. 2018, PMID 29362030) and of diagnosis and treatment (Talusan et al. 2014, PMID 24319044). The physiotherapy-facing anchor is a report of conservative treatment using foot orthoses (Longworth et al. 2019, PMID 31704590), and the return-to-sport anchor is a study of provider-cleared return to sport after Freiberg infraction in adolescent athletes (Touban et al. 2026, PMID 42474446).

PubMed Source

The Cartilage paper is an evidence-based treatment algorithm, not a clinical practice guideline, and it is written from a surgical perspective. The conservative literature in our library is a single orthotic report.

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Sources · 20

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Every source on this page resolves and title-verifies against PubMed. Newest first.

  1. 2023Katwal et al. (2023). Bilateral Freiberg disease in a young female dancer: A case report. SAGE open medical case reports, 11, 2050313X231221464. https://doi.org/10.1177/2050313X231221464
  2. 2023Oliveira et al. (2023). Freiberg disease: A rare cause of chronic foot pain. Reumatologia clinica, 19(6), 348. https://doi.org/10.1016/j.reumae.2022.11.006
  3. 2026Ottofaro et al. (2026). Metatarsophalangeal Joint Osteoarthritis of the Lesser Toes and Freiberg Disease: A Contemporary Review. Foot & ankle international, 47(3), 324-332. https://doi.org/10.1177/10711007251401532
  4. 2026El Yaagoubi et al. (2026). Bloodpool and Late-Phase 3D-Ring CZT SPECT/CT in Freiberg Disease. Clinical nuclear medicine, 51(8), 712-713. https://doi.org/10.1097/RLU.0000000000006487
  5. 1967Smillie (1967). Treatment of Freiberg's infraction. Proceedings of the Royal Society of Medicine, 60(1), 29-31. https://doi.org/10.1177/003591576706000117
  6. 2014Talusan et al. (2014). Freiberg's infraction: diagnosis and treatment. Foot & ankle specialist, 7(1), 52-6. https://doi.org/10.1177/1938640013510314
  7. 2018Seybold & Zide (2018). Treatment of Freiberg Disease. Foot and ankle clinics, 23(1), 157-169. https://doi.org/10.1016/j.fcl.2017.09.011
  8. 2019Longworth et al. (2019). Conservative treatment of Freiberg's infraction using foot orthoses: A tale of two prescriptions presented as a case study to open debate. Foot (Edinburgh, Scotland), 41, 59-62. https://doi.org/10.1016/j.foot.2019.07.002
  9. 2024Yoshimura et al. (2024). Evidence-Based Treatment Algorithm for Freiberg Disease. Cartilage, 15(1), 58-64. https://doi.org/10.1177/19476035231205676
  10. 2015Schade (2015). Surgical Management of Freiberg's Infraction: A Systematic Review. Foot & ankle specialist, 8(6), 498-519. https://doi.org/10.1177/1938640015585966
  11. 2019Georgiannos et al. (2019). Osteochondral Autologous Transplantation Versus Dorsal Closing Wedge Metatarsal Osteotomy for the Treatment of Freiberg Infraction in Athletes: A Randomized Controlled Study With 3-Year Follow-up. The American journal of sports medicine, 47(10), 2367-2373. https://doi.org/10.1177/0363546519859549
  12. 2020Kim et al. (2020). Comparison of Osteochondral Autologous Transplantation and Dorsiflexion Closing Wedge Metatarsal Osteotomy for Late-Stage Freiberg Disease in Adults. Foot & ankle international, 41(5), 529-535. https://doi.org/10.1177/1071100720904363
  13. 2025Incesoy et al. (2025). Comparative study of dorsiflexion closing wedge osteotomy of the metatarsal head and osteochondral autologous transplantation for Freiberg disease treatment: A multicenter analysis. The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons, 64(2), 113-119. https://doi.org/10.1053/j.jfas.2024.09.009
  14. 2024Kim et al. (2024). Short-Term Outcomes of Arthroscopic Treatment of Freiberg Disease. Journal of the American Podiatric Medical Association, 114(3). https://doi.org/10.7547/22-025
  15. 2019Lui & Fan (2019). Arthroscopic Dorsal Closing-Wedge Osteotomy of Metatarsal Head for Management of Freiberg Infraction. Arthroscopy techniques, 8(11), e1289-e1293. https://doi.org/10.1016/j.eats.2019.07.003
  16. 2020Çevik et al. (2020). Interpositional Arthroplasty With Extensor Digitorum Brevis Tendon in Freiberg Disease. Foot & ankle international, 41(11), 1398-1403. https://doi.org/10.1177/1071100720938769
  17. 2020Dhar et al. (2020). Surgical Management of Freiberg Disease by Dorsal Closing Wedge Osteotomy. Malaysian orthopaedic journal, 14(3), 161-165. https://doi.org/10.5704/MOJ.2011.025
  18. 2013Lee et al. (2013). Operative treatment of Freiberg disease using extra-articular dorsal closing-wedge osteotomy: technical tip and clinical outcomes in 13 patients. Foot & ankle international, 34(1), 111-6. https://doi.org/10.1177/1071100712460185
  19. 1993Sproul et al. (1993). Surgical treatment of Freiberg's infraction in athletes. The American journal of sports medicine, 21(3), 381-4. https://doi.org/10.1177/036354659302100309
  20. 2026Touban et al. (2026). Provider-Cleared Return-to-Sport After Freiberg Infraction in Adolescent Athletes. Journal of pediatric orthopedics. https://doi.org/10.1097/BPO.0000000000003420

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